منابع مشابه
Vascular adaptations to pregnancy in mice: effects on myogenic tone.
The mechanisms underlying vascular adaptations in pregnancy remain to be fully elucidated. One of the contributory mechanisms for reduced vascular tone may be a reduction of myogenic tone. Myogenic tone was assessed as the difference between internal diameter in the presence and absence of external calcium at different intramural pressure steps (60-100 mmHg). Myogenic responses were reduced in ...
متن کاملSignaling mechanisms underlying the vascular myogenic response.
The vascular myogenic response refers to the acute reaction of a blood vessel to a change in transmural pressure. This response is critically important for the development of resting vascular tone, upon which other control mechanisms exert vasodilator and vasoconstrictor influences. The purpose of this review is to summarize and synthesize information regarding the cellular mechanism(s) underly...
متن کاملRegulation of vascular tone, molecular mechanisms.
V ASCULAR tone, a state of maintained contraction of the smooth muscle in the vessel wall, is the process by which the blood vessel carries out its physiologic functions, its pharmacologic responses, and its pathologic changes. Current research directed at an understanding of the molecular mechanisms that regulate vascular tone is progressing at a rapid rate. The state of this art was surveyed ...
متن کاملMyogenic tone in isolated perfused vessels. Occurrence among vascular beds and along vascular trees.
In situ studies yield only indirect evidence as to whether non-neurogenic vascular tone results from an intrinsic myogenic tendency of the smooth muscle cell to contract or is due to stimulation of the muscle by some vasoactive humoral influence of the environment. In the current study, small resistance vessels from different vascular beds, from various levels of the arterial tree, and from sev...
متن کاملRegulation of vascular tone: role of 20-HETE in the modulation of myogenic reactivity.
Bayliss 1 first suggested that distention (stretch) of the vascular wall, elicited by increases in intravascular pressure, acts as a facilitating stimulus on the vascular smooth muscle (VSM) to intensify its activity, eliciting constriction of blood vessels. Since this original hypothesis was offered, it has been recognized that this pressuresensitive response, a constriction to elevation and a...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1997
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)44605-2